News

Genetic Mutation of HARs and Human Neurocognition

8/5/2013

Genetic Mutation of HARs and Human Neurocognition

8/5/2013

Investigator: Dr. Evan Eichler
Institution: University of Washington
Project Title: “Genetic Mutation of HARs and Human Neurocognition”
Award Amount: $493,000 (2013)

Dr. Evan Eichler is one of three ADI researchers the Foundation selected in 2013 that is investigating the genomic regions that are highly conserved but uniquely mutated in humans (Human Accelerated Regions or “HARs”) and their functional significance. This is unchartered territory and the research could help bring us one step closer in understanding what makes us human, and perhaps uncover insight into mutations that cause disease. This investigator will use human genetics to narrow down the spectrum of HARs to a set of regions associated to human developmental and cognitive disorders that affect the cortex, in aim to find which HARs may be associated with disability and autism.