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Molecular and genetic analysis of human brain evolution

8/5/2013

Molecular and genetic analysis of human brain evolution

8/5/2013

Investigator: Dr. Christopher Walsh
Institution: Boston Children’s Hospital
Project Title: “Molecular and Genetic Analysis of Human Brain Evolution”
Award Amount: $750,000

Dr. Christopher Walsh is one of three ADI researchers the Foundation selected in 2013 that is investigating the genomic regions that are highly conserved but uniquely mutated in humans (Human Accelerated Regions or “HARs”) and their functional significance. This is unchartered territory and the research could help bring us one step closer in understanding what makes us human, and perhaps uncover insight into mutations that cause disease. This investigator will attempt to better understand human brain function, by looking at the cerebral cortex to determine the functional significance of genes involved in its folding.